Verifynow p2y12 assay user manual

Comparison of verifynowp2y12 test and flow cytometry for. Pdf comparison of verifynowp2y12 test and flow cytometry for. P2y12 reaction unit pru, measured in adppge1 channel, reports adpmedicated aggregation specific to p2y12 receptor. Evaluation of the same patients with the verifynowp2y12 test revealed that the area under the. Whole blood was processed according to the user s manual of verifynow system accumetrics, san diego, ca, usa. The verifynow platform is one of the most user friendly pointofcare platelet function. P2y12 test united clinical laboratories test catalog. Assessment of verifynow p2y12 assay accuracy in evaluating clopidogrelinduced platelet inhibition article in therapeutic drug monitoring 303. J about this manual this user manual is the place to begin if you are not familiar with the verifynow instrument. Verifynow platelet inhibition uw laboratory test guide. Verifynow system instrumentation laboratory worldwide. Suggested timing for testing patients on p2y12 inhibitory drugs is. About this manual verifynow system user manual page 6 14340.

Verify now p2y12 assay for antiplatelet effect laboratory test. About this manual about this manual this user manual is the place to begin if you are not familiar with the verifynow instrument. Verifynow p2y12 assay is not intended for use with these types. Samples should be collected 2 to 30 hours after ingestion of aspirin to show drug effect.

A gene on chromosome 3q24q25 that encodes a g proteincoupled receptor for various drugs as well adenosine and uridine nucleotides. Millions of americans use aspirin andor a p2y12 inhibitor drug for antithrombotic therapy or thrombotic prophylaxis. The verifynow aspirin assay is a qualitative test to aid in the detection of platelet dysfunction due to aspirin asa ingestion in citrated whole blood for the point of care or laboratory setting. Verifynow prutest measures the level of platelet p2y12. Article in thrombosis and haemostasis 1116 march 2014 with 64 reads how we measure reads. Patients who have been treated with aggrastat or integrilin within two days or reopro within two weeks should not be tested. For help with use of this instrument, please contact your laboratory supervisor or your accumetrics customer support representative. The verifynow system is a turbidometric based optical detection system, which measures. Does the verifynow p2y12 assay overestimate therapeutic response to clopidogrel. This is a test for p2y12 inhibition by clopidogrel plavix, prasugel effient, or ticlopidine ticlid. For help with use of this instrument, please contact your laboratory supervisor or your. Evaluation of the same patients with the verifynowp2y12 test.

An assay of measuring platelet reactivity using monoclonal. Verifynow prutest measures the level of platelet p2y12 receptor blockade to help identify patient response to antiplatelet therapy, including clopidogrel plavix, prasugrel effient and ticagrelor brilinta. The verifynow p2y12 assay is comprised of the verifynow p2y12 cartridge, wet quality controls 1 and 2, and the verifynow instrument and electronic quality control. Base is an independent measurement based on platelet aggregation from.

Assessment of verifynow p2y12 assay accuracy in evaluating. The verifynow p2y12 assay is designed to be run on the verifynow instrument. Verifynow aspirin test aids in assessing how aspirin is affecting platelets, allowing rapid, informed treatment decisions. Verifynow system offers platelet reactivity results in minutes, providing antiplatelet therapy guidance in many clinical settings, including the operating room, cardiac catheterization lab, interventional radiology.

The reference range for individuals not receiving a p2y12 inhibitor is 180376 pru. Aids in assessing how aspirin is affecting platelets, allowing rapid, informed treatment decisions. P2y12 assay fairview diagnostic laboratories fairview health. The assay assesses the efficacy of platelet aggregation inhibition by the thienopyridine class of drugs that act by blocking the p2y12 receptor site.